About PHENTERMINE

• INDICATIONS AND USAGE

  PHENTERMINE hydrochloride is indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity.

• CONTRAINDICATIONS

  Advanced arteriosclerosis, cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma.

  Agitated states.

  Patients with a history of drug abuse.

  During or within 14 days following the administration of monoamine oxidase inhibitors (hypertensive crises may result).

• DOSAGE AND ADMINISTRATION

  Dosage should be individualized to obtain an adequate response with the lowest effective dose.

  Exogenous Obesity:

  CAPSULES: The usual adult dose is one capsule (37.5 mg) daily, administered before breakfast or 1-2 hours after breakfast.

  TABLETS: The usual adult dose is one tablet (37.5 mg) daily, administered before breakfast or 1 to 2 hours after breakfast. The dosage may be adjusted to the patient's need. For some patients ½ tablet (18.75 mg) daily may be adequate, while in some cases it may be desirable to give ½ tablet (18.75 mg) two times a day.

  PHENTERMINE hydrochloride is not recommended for use in patients 16 years of age and under.

• HOW IT'S SUPPLIED

  Mutual Pharmaceutical (manufature)

  PHENTERMINE hydrochloride tablets USP 37.5 mg (equivalent to 30 mg PHENTERMINE base) are white with blue specks, oval shaped, scored on one side and debossed MP 273 on the other side.

  KVK-TECH INC. (manufacture)

  PHENTERMINE hydrochloride capsules, USP 37.5 mg are supplied as bright blue opaque cap, white opaque body with black imprint "K29" on both cap and body, filled with powder.

  PHENTERMINE hydrochloride tablets USP 37.5 mg (equivalent to 30 mg PHENTERMINE base) are supplied as blue and white mottled oval tablets debossed "K" left to bisect "25" on one side and plain on the other side.

  Apotheca, Inc. (Repackager and Distributer)

  PHENTERMINE HCl 37.5 mg tablets USP (white with blue specks) are available as follows:

  • NDC 12634-687-91 Blister Pack UD
  • NDC 12634-687-97 Bottle of 7
  • NDC 12634-687-84 Bottle of 14
  • NDC 12634-687-85 Bottle of 15
  • NDC 12634-687-78 Bottle of 28
  • NDC 12634-687-71 Bottle of 30
  • NDC 12634-687-60 Bottle of 60

  PHENTERMINE HCl 37.5 mg capsules USP (bright blue cap with white opaque body) are available as follows:

  • NDC 12634-553-91 Blister Pack UD
  • NDC 12634-553-97 Bottle of 7
  • NDC 12634-553-84 Bottle of 14
  • NDC 12634-553-85 Bottle of 15
  • NDC 12634-553-78 Bottle of 28
  • NDC 12634-553-71 Bottle of 30
  • NDC 12634-553-60 Bottle of 60

PHENTERMINE Discount Card

Frequently Asked Questions

• How does the PHENTERMINE Prescription Discount Card work?

  PhentermineSavings.com is partnered with companies that negotiate discounts directly with the pharmacies. These discounts are then passed directly on to cardholders.

• Who is eligible for the PHENTERMINE Prescription Discount Card?

  The PHENTERMINE Prescription Discount Card has no requirements. Unlike insurance programs, there is no income, age, pre-existing condition, deductible, or waiting period restrictions. The free discount card is designed to help patients nationwide who do not have prescription drug coverage or who have coverage but are subject to large deductibles, large co-pays, formulary limitations, dosing limitations, gaps, and/or any cash out-of-pocket expenses.

• How much does the PHENTERMINE Prescription Discount Card/Coupon cost?

  The PHENTERMINE Prescription Discount Card is absolutely FREE. We provide this service to every American that wishes to save on their PHENTERMINE prescription cost. There are no premiums or deductibles associated with this program whatsoever. The printable card/coupon is available free of charge from our website.

• How do I use the PHENTERMINE Prescription Discount Card?
  1. Select a pharmacy: the PHENTERMINE Prescription Discount Card is valid at over 68,000 network pharmacy locations nationwide. In most cases, your current pharmacy will be part of our network.
  2. Submit your prescription: Present your PHENTERMINE prescription to the pharmacist. If you need to transfer a prescription, bring your empty prescription bottle or label with you to the pharmacy.
  3. Present your PHENTERMINE Prescription Discount Card: Your card's unique code provides the pharmacist with the appropriately discounted prescription price. The price on the prescription is based on the pharmacy's contracted agreement with PhentermineSavings.com and our partners.
  4. You Save: Your savings will be clear once the pharmacist enters your filled prescription into the register. Whether the lowest discount price is the PHENTERMINE Prescription Discount Card price, your present insurance program's price, or the pharmacy's already discounted price, you are GUARANTEED to receive the LOWEST price available!
• Which pharmacies can I go to?

  We have a constantly expanding list of over 68,000 participating major chain pharmacies and local pharmacies nationwide including CVS/Pharmacy, Walgreens, Target Pharmacy, Walmart Pharmacy, Safeway, Rite Aid, and more!

• How can I be assured I am getting the lowest price?

  The discounted price may vary by as much as 75% depending on the pharmacy discount rate contracted with PhentermineSavings.com. While pharmacy prices may vary from week-to-week and by the geographic location, the patient is guaranteed the lowest price available regardless of whether it is the PhentermineSavings.com price, your present insurance program's price, or the pharmacy's already discounted price.

PHENTERMINE Safety Information

• WARNINGS

  Phentermine hydrochloride tablets are indicated only as short-term monotherapy for the management of exogenous obesity. The safety and efficacy of combination therapy with phentermine and any other drug products for weight loss, including selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. Therefore, coadministration of these drug products for weight loss is not recommended.

  Primary Pulmonary Hypertension (PPH) - a rare frequently fatal disease of the lungs - has been reported to occur in patients receiving a combination of phentermine with fenfluramine or dexfenfluramine. The possibility of an association between PPH and the use of phentermine alone cannot be ruled out; there have been rare cases of PPH in patients who reportedly have taken phentermine alone. The initial symptom of PPH is usually dyspnea. Other initial symptoms include: angina pectoris, syncope or lower extremity edema. Patients should be advised to report immediately any deterioration in exercise tolerance. Treatment should be discontinued in patients who develop new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema.

  Valvular Heart Disease: Serious regurgitant cardiac valvular disease, primarily affecting the mitral, aortic and/or tricuspid valves, has been reported in otherwise healthy persons who had taken a combination of phentermine with fenfluramine or dexfenfluramine for weight loss. The etiology of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known. The possibility of an association between valvular heart disease and the use of phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken phentermine alone.

  Tolerance to the anorectic effect usually develops within a few weeks. When this occurs, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued.

  Phentermine hydrochloride may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly.

  Usage with Alcohol: Concomitant use of alcohol with phentermine hydrochloride may result in an adverse drug interaction.

• PRECAUTIONS

  Caution is to be exercised in prescribing phentermine hydrochloride for patients with even mild hypertension.

  Insulin requirements in diabetes mellitus may be altered in association with the use of phentermine hydrochloride and the concomitant dietary regimen.

  Phentermine hydrochloride may decrease the hypotensive effect of guanethidine.

  The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage.

  Carcinogenesis, Mutagenesis, Impairment of Fertility Studies have not been performed with phentermine hydrochloride to determine the potential for carcinogenesis, mutagenesis or impairment of fertility

  PregnancyTeratogenic Effects: Pregnancy Category C. Animal reproduction studies have not been conducted with phentermine hydrochloride. It is also not known whether phentermine hydrochloride can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. Phentermine hydrochloride should be given to a pregnant woman only if clearly needed.

  Nursing MothersBecause of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

  Pediatric UseSafety and effectiveness in pediatric patients have not been established.

• SIDE EFFECTS

  Cardiovascular: Primary pulmonary hypertension and/or regurgitant cardiac valvular disease (see WARNINGS), palpitation, tachycardia, elevation of blood pressure.

  Central Nervous System: Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, rarely psychotic episodes at recommended doses.

  Gastrointestinal: Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances.

  Allergic: Urticaria.

  Endocrine: Impotence, changes in libido.

• DRUG ABUSE AND DEPENDENCE

  Phentermine hydrochloride is related chemically and pharmacologically to the amphetamines. Amphetamines and related stimulant drugs have been extensively abused, and the possibility of abuse of phentermine hydrochloride should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. The most severe manifestation of chronic intoxications is psychosis, often clinically indistinguishable from schizophrenia.

• OVERDOSAGE

  Manifestations of acute overdosage with phentermine include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmias, hypertension or hypotension and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps. Fatal poisoning usually terminates in convulsions and coma.

  Management of acute phentermine intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard. Acidification of the urine increases phentermine excretion. Intravenous phentolamine has been suggested for possible acute, severe hypertension, if this complicates phentermine overdosage.